TB-500 10mg

Description

TB-500 is a synthetic peptide fragment of Thymosin Beta-4, primarily researched for its role in cellular migration and tissue regeneration.

TB-500 is a synthetic version of the naturally occurring peptide Thymosin Beta-4, a 43-amino acid protein found in high concentrations in most human and animal tissues. In research settings, TB-500 is extensively studied for its potential role in tissue repair, cellular migration, and angiogenesis. Unlike other growth factors, TB-500 possesses a low molecular weight, which laboratory models suggest may allow for greater mobility through tissues to reach sites of injury. Scientific investigation into TB-500 focuses primarily on its ability to upregulate actin, a vital protein for cell structure and movement. By modulating actin levels, researchers observe how the peptide influences the migration of cells to assist in the recovery of connective tissues, including tendons, ligaments, and muscle fibers. Its unique sequence is also a primary subject of interest in studies regarding corneal repair and cardiac tissue regeneration following ischaemic events.

Product Overview

TB-500 (Thymosin Beta-4) is a synthetic peptide fragment that mimics the active region of the endogenous protein. It is widely recognised in biochemical research for its influence on the actin cytoskeleton. This product is provided as a highly purified lyophilised powder, ensuring structural stability for precise laboratory experimentation.

Specifications

Form: Lyophilised Powder Molecular Formula: C212H350N56O78S1 Purity: ≥99% (HPLC verified) Quantity: 10mg Storage: Store in a cool, dry place, away from direct sunlight. Once reconstituted, the product should be kept refrigerated and used within a specific research timeframe.

Research Applications

Research into TB-500 is focused on its multi-faceted role in cellular repair. Key areas of study include: - Upregulation of actin for enhanced cellular migration. - Influence on angiogenesis (new blood vessel formation) in damaged tissues. - Modulation of inflammatory chemokines and cytokines. - Protective effects on dermal and corneal tissues in animal models. - Potential for accelerating myofibrillar repair in skeletal muscle studies.

Research Use Notice

For laboratory research use only. Not for human or veterinary use.