SS-31 10mg

Description

SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide used in research to study cellular bioenergetics and oxidative stress regulation.

SS-31, also known as Elamipretide, is a synthetic tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that belongs to the Szeto-Schiller (SS) family of compounds. This peptide is unique for its ability to selectively target cardiolipin, a phospholipid located exclusively on the inner mitochondrial membrane. In contemporary biochemical research, SS-31 is extensively studied for its potential to stabilize mitochondrial structure and promote efficient electron transport chain function under conditions of oxidative stress. Scientific investigations focus on how SS-31 penetrates cell membranes independently of membrane potential to interact with the mitochondria. Researchers utilize this compound to observe its impact on the reduction of reactive oxygen species (ROS) production and the prevention of mitochondrial permeability transition pore (mPTP) opening. Its role as a mitochondria-targeted antioxidant makes it a subject of significant interest in cellular bioenergetics and metabolic research.

Product Overview

SS-31 (Elamipretide) is a cell-permeable peptide designed to target the inner mitochondrial membrane. Unlike many antioxidants that accumulate based on membrane potential, SS-31 binds directly to cardiolipin, helping to maintain mitochondrial cristae structure. This product is intended strictly for laboratory research and in vitro experimentation.

Specifications

Chemical Name: Elamipretide Sequence: D-Arg-Dmt-Lys-Phe-NH2 Molecular Formula: C32H49N9O5 Form: Lyophilised White Powder Quantity: 10mg Purity: ≥99% (HPLC) Storage: Store in a cool, dry place, away from direct light. For long-term storage, keep at -20°C.

Research Applications

Research involving SS-31 primarily explores its influence on mitochondrial dysfunction and oxidative damage. Published literature focuses on its application in models of ischemia-reperfusion injury, neurodegenerative pathways, and age-related metabolic decline. It is widely used in studies assessing mitochondrial respiration efficiency and the preservation of ATP synthesis in stressed cellular environments.

Research Use Notice

For laboratory research use only. Not for human or veterinary use.