
GulfBio · GB-NADPLUS-500MG
NAD+ 500mg
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Description
A high-purity research coenzyme studied for its critical role in mitochondrial energy production, DNA repair, and cellular signaling pathways.
Nicotinamide Adenine Dinucleotide (NAD+) is a vital coenzyme found in all living cells, serving as a critical component in electron transfer reactions. As a key derivative of vitamin B3, NAD+ exists in two forms: NAD+ (the oxidized form) and NADH (the reduced form). In scientific research, this molecule is extensively studied for its central role in energy metabolism, particularly within the mitochondrial respiratory chain where it facilitates the production of Adenosine Triphosphate (ATP). Beyond its metabolic functions, NAD+ is a fundamental substrate for several classes of enzymes, including sirtuins (SIRT) and poly(ADP-ribose) polymerases (PARPs). These enzymes are involved in maintaining genomic stability and regulating cellular responses to oxidative stress. Research focusing on NAD+ aims to understand the mechanisms of cellular aging, DNA repair efficiency, and the maintenance of mitochondrial homeostasis in various biological models.
Product Overview
NAD+ (Nicotinamide Adenine Dinucleotide) is a foundational coenzyme required for biological oxidation and reduction reactions. It acts as a major electron carrier in the metabolic processes that convert nutrients into cellular energy. In laboratory settings, NAD+ is utilized to study cellular signaling pathways and the biochemical triggers associated with metabolic decline and cellular senescence.
Specifications
Form: Lyophilised Powder Quantity: 500mg Purity: Greater than 99% as determined by HPLC analysis Storage: Store in a cool, dry place, away from direct light. For long-term stability, ensure the vial remains sealed until required for research applications.
Research Applications
Current research involving NAD+ focuses on its capacity to act as a signaling molecule in the regulation of biological pathways. Investigators study its influence on sirtuin activation, which is linked to gene expression and cellular longevity. Additionally, NAD+ is a primary subject in studies regarding neuroprotection, mitochondrial biogenesis, and the metabolic impact of NAD+ depletion in aging tissues.
Certificate of Analysis
Review the batch documentation for identity and purity details.
COAs available upon request — contact GulfBio Support.
Research Use Notice
For laboratory research use only. Not for human or veterinary use.
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